Yersinia pestis

Plague in San Francisco in Loss of the pigmentation phenotype in Yersinia pestis is due to the spontaneous deletion of kb of chromosomal DNA which is flanked by a repetitive element. Yersinia pestis infection in Vietnam. Asia Pandemic that spread to Europe killed about 75 million people.

S Afr Med J. But outbreaks today Yersinia pestis few and isolated. The researchers reported that the Y. A scene of death and despair in a London street during the plague outbreak of —66, which killed more than 70, people. It is sometimes presumed to be the disease behind several historic epidemics, such as the pestilence described as striking the Philistines in the biblical book of 1 Samuel.

If treatment is delayed for too long, Yersinia pestis can spread throughout the body as secondary septicemic plague, which can result in massive, systematic damage.

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Nature of the disease Plague is primarily a disease of rodents, and humans enter only accidentally into the usual cycle. Plague pandemics investigated by ribotyping of Yersinia pestis strains.

Yersinia pestis

Clinical features Symptoms The symptoms of Yersinia pestis present in different ways, but the three most common are bubonic, septicemic, and pneumonic plague.

In Yunnan, Chinainhabitants would flee from their homes as soon as they saw dead rats, and on the island of Formosa Taiwanresidents considered the handling of dead rats heightened the risks of developing plague. Avoid contact with the nests and burrows of squirrels, chipmunks and other rodents.

However, the selection of antibiotic therapy is crucial, as several classes of antibiotics have proven to be ineffective in treatment for the plague.

Yersin named the new bacillus Pasteurella pestis, after his mentor, but in the bacterium was renamed Yersinia pestis, in honour of Yersin himself.

The researchers reported that the Y. Plasmid content in Yersinia pestis strains of different origin. Effector Yersinia outer proteins Yops interfere with host cell signaling [16].

Black Death (Yersinia pestis)

Beginning in the s, sulfa drug s and then antibiotics such as streptomycin gave doctors a very effective means of attacking the plague bacillus directly.

Genetic analysis of the low calcium response in Yersinia pestis mu d1 Ap lac insertion mutants. Restoration of functional ureD rendered Y. Since scientists were able to sequence the genome, they now have information of how diseases caused by this pathogenic bacteria develop and also the evolutionary history of the bacteria.

Yersinia pestis pH 6 antigen: Colonization and growth of Y. The host is immune to virulent rechallenge, the inoculum being eliminated as though the organisms were completely avirulent". Dogs and cats may also bring plague-infected fleas into the home.

Plague (Yersinia Pestis)

Geneticheskii analiz i modelirovanie virulentnosti Yersinia pestis. Mutation rate estimates for these VNTR markers are of importance because their relatively rapid evolution can be used to study the population dynamics of plague outbreaks within natural rodent populations Nucleotide sequence of the Yersinia pestis gene encoding F1 antigen and the primary structure of the protein.


Yersinia Pestis (Pathogenesis)

Plague or black death is an infection of rodents caused by Yersinia pestis and accidentially transmitted to humans by the bite of infected fleas. The disease follows urban and sylvatic cycles and is manifested in bubonic and pneumonic forms [note: bubo is derived from a Greek word for groin].

Plague: Plague, infectious disease caused by Yersinia pestis, a bacterium transmitted from rodents to humans by the bite of infected fleas. Life History Yersinia pestis is the causative agent of the systemic invasive infectious disease often referred to as the plague.

The Y. pestis is an extremely virulent pathogen that is likely to cause severe illness and death upon infection unless antibiotics are the past, Y. pestis has caused devastating epidemics during three periods of modern history; the Justinian Plague. Classification Higher order taxa.

Kingdom: Eubacteria Phylum: Proteobacteria Class: Gamma Proteobacteria Order: Enterobacteriale Genus: Yersinia Species.

Yersinia pestis--etiologic agent of plague.

Yersinia pestis. Description and significance. Yersinia pestis was discovered in Hong Kong in by a Swiss physician Alexandre Yersin, who was a student of the Pasteur school of thought. He linked Y. pestis to the bubonic. Plague is a disease that affects humans and other mammals. It is caused by the bacterium, Yersinia usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague.

Description. Yersinia pestis is a zoonotic pathogen that is most commonly transmitted through fleas that feed on infected rodents.Y. pestis is a Gram-negative, non-motile, non-spore-forming coccobacillus that is also a facultative anaerobe.

In the past, this pathogen ravaged cities throughout Europe, Asia, and Africa, takin thousands of lives with sudden outbreaks.

Yersinia pestis
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Black Death (Yersinia pestis)